The Collaboratory Conversation Series episode Community Engagement and Informed Consent – A Conversation with Azure Hermes talked about a couple of concepts that are really important ethical underpinnings to co-creative processes that work across differentials of power – the principles of Free, Prior & Informed Consent (FPIC) and Iterative Consent. In this article we dive a bit deeper into these concepts and how the National Centre for Indigenous Genomics (NCIG) have communicated and engaged with First Nations community members to achieve these principles in practice.